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Generating Ampicillin-Level Antimicrobial Peptides with Activity-Aware Generative Adversarial Network
Friday Nov 13 2020 00:30 GMT
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Generating Ampicillin-Level Antimicrobial Peptides with Activity-Aware Generative Adversarial Network
Why This Is Interesting

Antibiotic resistance is a serious and immediate threat against humanity as currently available antibiotics become increasingly obsolete. Antimicrobial peptides are a possible solution to this problem. This talk will be about a peptide-specialized generative model called PepGAN that takes the balance between covering active peptides and dodging nonactive ones.

Discussion Points

– PepGAN set-up – Generated peptide statistical and in vitro validation

Takeaways
  • Deep learning for generating proteins allow potential drug discovery.
  • Reinforcement learning approach to training GAN to achieve a better performance
Time of Recording: Friday Nov 13 2020 00:30 GMT